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This site uses the Algorithm Specification Interface (ASI) as a programming platform
to aid in the encoding of genotypic drug resistance interpretation involving HIV.
The DMC implementation of ASI allows us to focus and continually improve our analysis algorithm.
This project is a result of a collaboration between Dr. Rodger MacArthur (WSU), Dr. Hossein Salimnia (DMC), and the
staff of the
Applied Genomics Techonolgy Center (WSU). We would also like to thank Dr. Robert Shaffer
(Stanford University) for their
development and support of the ASI standard.
Please note that no information is stored or collected on the system.
Analyze a Sequence using the DMC Algorithm
(Best used with Internet Explorer)
Help Page
Feel free to use these sample input files:
Sample 1
Sample 2
Sample 3
Please send all inquiries to Dr. Rodger MacArthur
References:
MacArthur RD. An updated guide to genotype interpretation.
AIDS Reader 2004;14(5):256-66.
Sturmer M, Doerr HW, Staszewski S, Preiser W. Comparison of nine resistance
interpretation systems for HIV-1 genotyping. Antivir Ther 2003;8(3):239-44.
Lanier ER, Scott J, Ait-Khaled M, et al. Predicting abacavir antiviral
activity using HIV-1 reverse transcriptase genotype; a comparison of 16
algorithms. 5th International Workshop on HIV Drug Resistance & Treatment
Strategies; Scottsdale, Arizona, June 2001, Abstract #137.
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